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Corona and thrombosis

Project summary

Many corona patients in intensive care (IC) develop venous thrombosis and pulmonary embolism. At least a third of all patients are affected. This is evident from collected data from Dutch hospitals. Patients who develop pulmonary embolism have a poorer prognosis and seem to die more often, therefore corona patients in ICU are treated with a higher dose of anticoagulant (than “regular” patients) in hopes of improving the prognosis. But much is still unclear and needs further investigation. For example, it is unclear whether patients develop thrombosis because they are frozen in the ICU with an infection, or whether the coronavirus itself causes more thrombosis. It is also not yet clear which treatment is best, and whether the administration of more anticoagulants also gives a better outcome.

Impact

This study may also provide important data for the (future) treatment of pulmonary embolism in patients who do not have COVID-19.

More detailed information

Principal Investigator:

Role Erasmus MC:

Coördinator

Department:

Hematology

Project website:

Not available

Funding Agency:

Trombose Stichting Nederland