Cellular stress: A novel target for the immune therapy of cancer
In this project, we oppose the current mainstream idea that personalized therapies are the most promising solution to fight cancer. Instead, we show evidence for molecular mechanisms that could be harnessed to develop novel treatment regimens with broader specificity. We will investigate cellular stress as a shared feature of cancer and hypothesize that common stress-related “errors” in the production of cellular proteins could serve as novel targets for non-personalized immune therapies.
If successful, this project has the potential to establish a new research line with implications for the treatment of cancer, but also other diseases that involve cellular stress.
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Dr. C. Schliehe
Role Erasmus MC: