Enhancing health systems sustainability by providing cost-efficiency data based interventions for chronic management in stratified population based on clinical and socio-economic determinants of health (EFFICHRONIC)
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Project summary
Many neuropsychiatric disorders are treated using drugs that target the transmission of the neurotransmitter serotonin. However, the suboptimal efficacy of these drugs alongside new lines of research highlighting a role for serotonin in neurodevelopment have urged scientists to revisit the origins and treatment of these disorders. The EU-funded SEROTONIN and BEYOND project will work under the hypothesis that serotonin-related neuropsychiatric disorders are caused by neurodevelopmental changes. To address this scientific concept, the project will train early-stage researchers in state-of-the-art techniques, preparing them for a bright career in the field.
Impact
Our Early Stage Researchers will increase the level of critical knowledge in the multi-level trajectories through which serotonin shapes transdiagnostic behaviour and cognition during critical windows in brain development. Through the integration of neurotechnologies and preclinical-clinical research, new discoveries can be expected. Furthermore, the training we provide in S&B allows ESRs to deliver insights in critical windows for interventions as well as new ideas for future intervention approaches redirecting serotonin-mediated developmental changes. This will lead to improved prevention of these disorders and promote mental health.
More detailed information
Principal Investigator:
prof. Henning Tiemeier
Role Erasmus MC:
Partner
Department:
Project website:
Not available
Funding Agency:
H2020: Marie Sklodowska Curie
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