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To unravel how the CHEK2 c.1100delC mutation leads to breast cancer development through genome analysis and a human breast model.

Project summary

To unravel how the CHEK2 c.1100delC mutation leads to breast cancer development through genome analysis and a human breast model. Hollestelle delves into the underlying mechanism by which cells with a hereditary CHEK2 mutation can develop into breast cancer. Knowledge of this mechanism can eventually lead to prevention and better treatment of this cancer.

Impact

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More detailed information

Principal Investigator:

Dr. Antoinette Hollestelle

Role Erasmus MC:

Coördinator

Department:

Oncology

Project website:

Not available

Funding Agency:

KWF